| Ian Kinsler | 2B | 5/18/2013 | on 15-day DL | Right intercostal strain |
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| Alexi Ogando | P | 5/16/2013 | on 15-day DL | Right biceps tendinitis |
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| Justin Miller | P | 4/11/2013 | on 60-day DL | Recovery from right elbow surgery |
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| Matt Harrison | P | 4/7/2013 | on 60-day DL | Inflamed nerve in lower back |
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| Neftali Feliz | P | 3/24/2013 | on 60-day DL | Recovery from right elbow surgery |
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| Colby Lewis | P | 3/22/2013 | on 15-day DL | Recovery from right elbow surgery |
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| Joakim Soria | P | 3/22/2013 | on 15-day DL | Recovery from right elbow surgery |
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