R.A. Dickey lost on Opening Day and Jose Reyes is on the disabled list.
Stop me if you've heard this one before, because amazingly it's a scenario that Blue Jays fans are now experiencing for the second straight April.
Add in the fact that closer Casey Janssen was placed on the DL on the eve of the season, and you could argue things are even worse than they were a year ago for the Jays.
Let's get it out of the way right off the top - it was Game 1 of 162. A baseball fan wouldn't feel uncomfortable about a team's chances after just one game, right?
But there's no question that there's a sense of deja vu for Toronto fans after Monday's 9-2 loss to the Tampa Bay Rays. Bad starting pitching last April coupled with the injury to Reyes pretty much killed the Jays' chances at contending by the time the calendar flipped to May.
So is it an overreaction this time around to have that same ominous feeling that this is nothing more than a continuation of last season?
Sure, Tampa Bay is considered a World Series contender and there's no shame in losing to former Cy Young winner David Price.
In the 1989 baseball cult classic film "Major League", it was commentator Harry Doyle, played by the legendary Bob Uecker, who said "a lot of people say you can tell how the season's gonna go by the first hitter of the year."
Willie Mays Hays legged out an infield single for the Indians in the movie, then got picked off first base.
On Monday, Reyes never made it that far. In the first at-bat of the Blue Jays' season, he pulled up while running to first base after aggravating the hamstring injury that had been bothering him during spring training.
The team placed him on the 15-day disabled list after the game, meaning it will be the middle of the month at best before we see Toronto's star leadoff hitter in the lineup again.
The Blue Jays will play three more games at Tropicana Field this week, a place where they have not won a series since 2007. Then it's home for three against the revamped New York Yankees to close out the first week of the season.
Last year the Blue Jays finished the first week with a record of 2-4, and it's entirely possible they could be in that zone again.
Given, it's very, very early. You can't judge a major league season by the first game.
But do you feel uncomfortable about the Blue Jays after witnessing their Opening Day loss?
It's Your! Call.